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Table 2 Comparison of clinicopathological features between patients with Mt and Wt

From: Impact of the epidermal growth factor receptor mutation status on the prognosis of recurrent adenocarcinoma of the lung after curative surgery

Total n = 237

Mt (n = 108)

Wt (n = 129)

P valuesa

Age

66.5

66.1

0.791b

Male, (%)

48 (44.4)

85 (65.9)

0.001

Smoking history, (%)

52 (48.1)

94 (72.9)

< 0.001

Surgical procedure, (%)

 pneumonectomy

2 (1.9)

3 (2.3)

 

 lobectomy

104 (96.2)

124 (96.1)

 

 segmentectomy

2 (1.9)

2 (1.6)

0.958

Pathological tumor size, (mm)

33.9 (11–100)

40.0 (11–210)

0.019b

Pathological stage, (%)

 I

24 (22.2)

36 (27.9)

 

 II

26 (24.1)

36 (27.9)

 

 III

58 (53.7)

57 (44.2)

0.337

Lymphatic invasion, (%)

61 (56.4)

58 (45.0)

0.077

Vascular invasion, (%)

68 (63.0)

83 (64.3)

0.826

Pleural invasion, (%)

50 (46.3)

72 (55.8)

0.144

Nodal invasion, (%)

81 (75.0)

80 (62.0)

0.033

Recurrence pattern

 locoregional

29 (26.9)

43 (33.3)

 

 systemic

79 (73.1)

86 (66.7)

0.280

Administration of EGFR - TKI

81 (75.0)

7 (5.4)

< 0.001

  1. aFisher’s exact test
  2. bStudent’s t-test
  3. Mt EGFR mutant, Wt EGFR wild-type, TKI tyrosine kinase inhibitor