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Table 2 Univariate and Multivariate Analysis of Clinicopathological Characteristics in Relation to the Overall Survival in Patients with CRC Undergoing Curative Resection

From: Prognostic value of inflammation-based scores in patients receiving radical resection for colorectal cancer

 

Univariate

Multivariate

HR(95% CI)

p

HR(95% CI)

p

mGPS

1.49(1.129–1.965)

0.005

1.223(0.867–1.725)

0.253

SIS

1.5441.173–2.033)

0.002

0.869(0.562–1.345)

0.529

Albumin-NLR

1.812(1.35–2.433)

< 0.001

2.112(1.314–3.395)

0.002

Age

1.025(1.00701.044)

0.007

1.032(1.012–1.052)

0.001

TNM stage

2.251(1.553–3.263)

< 0.001

0.845(0.419–1.705)

0.638

T stage

1.674(1.162–2.412)

0.006

1.332(0.877–2.023)

0.179

N stage

1.759(1.397–2.241)

< 0.001

1.760(1.142–2.712)

0.01

TLN

0.425(0.276–0.654)

< 0.001

0.375(0.164–0.857)

0.02

NLN

0.383(0.248–0.591)

< 0.001

1.050(0.460–2.397)

0.908

Vascular invasion

2.501(1.606–3.893)

< 0.001

0.557(0.903–2.686)

0.111

Peripheral nerve invasion

1.732(1.046–2.868)

0.033

1.169(0.674–2.025)

0.578

Lymphocytes in invasive margin

0.396(0.249–0.63)

< 0.001

0.694(0.385–1.249)

0.223

Lymphocytes in central region

0.405(0.261–0.627

< 0.001

0.680(0.394–1.174)

0.167

  1. mGPS modified Glasgow Prognostic Score, SIS systemic inflammation score, albumin-NLR albumin- neutrophil-to-lymphocyte ratio; TLN total lymph nodes resected, NLN negative lymph nodes resected, HR hazard ratio, CI confidence interval