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Table 1 Patients’ Clinicopathological Characteristics and Associations with the mGPS, SIS and Albumin-NLR

From: Prognostic value of inflammation-based scores in patients receiving radical resection for colorectal cancer

   mGPS   SIS   Albumin-NLR  
All Case 0 1 2 P value 0 1 2 P value 0 1 2 P value
Cases 877 669 123 85   331 331 213   284 385 208  
Age 59(19–88) 59 59 62 0.064 57 60 62 < 0.001 57 60 61 0.001
Sex
 Male 533 391 87 55 0.027 197 194 142 0.122 179 225 129 0.445
 Female 344 278 36 30   134 139 71   105 160 79  
Location
 Right-sided colon 326 218 63 45 < 0.001 107 129 90 0.049 92 144 105 < 0.001
 Left-sided colon 551 451 60 40   224 204 123   192 241 103  
TNM stage
 I 106 95 6 5 < 0.001 51 38 17 0.065 49 41 16 0.001
 II 505 359 89 57   178 191 136   149 216 140  
 III 266 215 28 23   102 104 60   86 128 52  
T stage
 1 32 30 0 2 0.021 16 11 5 0.026 10 20 2 < 0.001
 2 99 36 8 5   46 35 18   48 32 19  
 3 598 446 92 60   219 239 140   181 276 141  
 4 148 107 23 18   50 48 50   45 57 46  
N stage
 0 602 447 93 62 0.179 223 226 153 0.739 196 251 155 0.232
 1 90 77 7 6   37 36 17   30 43 17  
 2 185 145 23 17   71 71 43   58 91 36  
TLN
 < 12 294 242 33 19 0.009 120 115 59 0.105 113 128 53 0.004
 > =12 583 427 90 66   211 218 154   171 257 155  
NLN
 < 11 293 237 34 22 0.073 120 112 61 0.184 108 128 57 0.047
 > =11 584 432 89 63   211 221 152   176 257 151  
Histology stage
 G1 8 6 2 0 0.08 3 3 2 0.589 1 6 1 0.167
 G2 626 489 77 61   244 230 152   208 277 141  
 G3 114 89 16 9   44 48 22   36 53 25  
 G4 128 85 28 15   40 52 36   39 48 41  
Nerve invasion
 No 725 548 101 76 0.224 261 276 188 0.018 234 308 183 0.049
 Yes 152 121 22 9   70 57 25   50 77 25  
Vascular invasion
 No   516 101 68 0.426 253 255 177 0.129 223 287 175 0.026
 Yes   153 22 17   78 78 36   61 98 33  
MSI status
 Deficient 89(10.1%) 51 26 12 < 0.001 29 22 38 < 0.001 26 28 35 0.001
 Proficient 788(89.9%) 618 97 73   302 311 175   258 357 173  
Neutrophil in central region
 Low 357 304 30 23 < 0.001 167 129 61 < 0.001 147 150 60 < 0.001
 High 520 365 93 62   164 204 152   137 235 148  
Neutrophil in invasive margin
 Low 561 445 66 50 0.014 243 205 113 < 0.001 200 251 110 < 0.001
 High 316 224 57 35   88 128 100   84 134 98  
Lymphocytes in central region
 Low   264 57 28 0.142 131 138 80 0.661 110 165 74 0.203
 High   405 66 57   200 195 133   174 220 134  
Lymphocytes in invasive margin
 Low 427 324 63 40 0.809 162 167 98 0.636 133 208 86 0.01
 High 450 345 60 45   169 166 115   151 177 122  
Crohn’s-like
 No 796 624 97 75 < 0.001 311 301 184 0.012 263 355 178 0.013
 Yes 78 43 25 10   19 31 28   21 28 29  
  1. mGPS modified Glasgow Prognostic Score, SIS systemic inflammation score, albumin-NLR albumin-neutrophil-to-lymphocyte ratio, TLN total lymph nodes resected, NLN negative lymph nodes resected, MSI microsatellite instability