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Table 1 Patients’ Clinicopathological Characteristics and Associations with the mGPS, SIS and Albumin-NLR

From: Prognostic value of inflammation-based scores in patients receiving radical resection for colorectal cancer

  

mGPS

 

SIS

 

Albumin-NLR

 

All Case

0

1

2

P value

0

1

2

P value

0

1

2

P value

Cases

877

669

123

85

 

331

331

213

 

284

385

208

 

Age

59(19–88)

59

59

62

0.064

57

60

62

< 0.001

57

60

61

0.001

Sex

 Male

533

391

87

55

0.027

197

194

142

0.122

179

225

129

0.445

 Female

344

278

36

30

 

134

139

71

 

105

160

79

 

Location

 Right-sided colon

326

218

63

45

< 0.001

107

129

90

0.049

92

144

105

< 0.001

 Left-sided colon

551

451

60

40

 

224

204

123

 

192

241

103

 

TNM stage

 I

106

95

6

5

< 0.001

51

38

17

0.065

49

41

16

0.001

 II

505

359

89

57

 

178

191

136

 

149

216

140

 

 III

266

215

28

23

 

102

104

60

 

86

128

52

 

T stage

 1

32

30

0

2

0.021

16

11

5

0.026

10

20

2

< 0.001

 2

99

36

8

5

 

46

35

18

 

48

32

19

 

 3

598

446

92

60

 

219

239

140

 

181

276

141

 

 4

148

107

23

18

 

50

48

50

 

45

57

46

 

N stage

 0

602

447

93

62

0.179

223

226

153

0.739

196

251

155

0.232

 1

90

77

7

6

 

37

36

17

 

30

43

17

 

 2

185

145

23

17

 

71

71

43

 

58

91

36

 

TLN

 < 12

294

242

33

19

0.009

120

115

59

0.105

113

128

53

0.004

 > =12

583

427

90

66

 

211

218

154

 

171

257

155

 

NLN

 < 11

293

237

34

22

0.073

120

112

61

0.184

108

128

57

0.047

 > =11

584

432

89

63

 

211

221

152

 

176

257

151

 

Histology stage

 G1

8

6

2

0

0.08

3

3

2

0.589

1

6

1

0.167

 G2

626

489

77

61

 

244

230

152

 

208

277

141

 

 G3

114

89

16

9

 

44

48

22

 

36

53

25

 

 G4

128

85

28

15

 

40

52

36

 

39

48

41

 

Nerve invasion

 No

725

548

101

76

0.224

261

276

188

0.018

234

308

183

0.049

 Yes

152

121

22

9

 

70

57

25

 

50

77

25

 

Vascular invasion

 No

 

516

101

68

0.426

253

255

177

0.129

223

287

175

0.026

 Yes

 

153

22

17

 

78

78

36

 

61

98

33

 

MSI status

 Deficient

89(10.1%)

51

26

12

< 0.001

29

22

38

< 0.001

26

28

35

0.001

 Proficient

788(89.9%)

618

97

73

 

302

311

175

 

258

357

173

 

Neutrophil in central region

 Low

357

304

30

23

< 0.001

167

129

61

< 0.001

147

150

60

< 0.001

 High

520

365

93

62

 

164

204

152

 

137

235

148

 

Neutrophil in invasive margin

 Low

561

445

66

50

0.014

243

205

113

< 0.001

200

251

110

< 0.001

 High

316

224

57

35

 

88

128

100

 

84

134

98

 

Lymphocytes in central region

 Low

 

264

57

28

0.142

131

138

80

0.661

110

165

74

0.203

 High

 

405

66

57

 

200

195

133

 

174

220

134

 

Lymphocytes in invasive margin

 Low

427

324

63

40

0.809

162

167

98

0.636

133

208

86

0.01

 High

450

345

60

45

 

169

166

115

 

151

177

122

 

Crohn’s-like

 No

796

624

97

75

< 0.001

311

301

184

0.012

263

355

178

0.013

 Yes

78

43

25

10

 

19

31

28

 

21

28

29

 
  1. mGPS modified Glasgow Prognostic Score, SIS systemic inflammation score, albumin-NLR albumin-neutrophil-to-lymphocyte ratio, TLN total lymph nodes resected, NLN negative lymph nodes resected, MSI microsatellite instability