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Table 1 IC50-values for PKIs against IGROV1 and SKOV3ip cells

From: Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma

  Alisertib Saracatinib MK1775 Temsirolimus MK2206
IGROV1 50 ± 3 nM n.a. 306 ± 4 nM n.a. n.a.
SKOV3ip 158 ± 3 nM n.a. 133 ± 4 nM 120 ± 4 nM 131 ± 3 nM
  1. Abbreviation: n.a. not available