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Table 1 IC50-values for PKIs against IGROV1 and SKOV3ip cells

From: Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma

 

Alisertib

Saracatinib

MK1775

Temsirolimus

MK2206

IGROV1

50 ± 3 nM

n.a.

306 ± 4 nM

n.a.

n.a.

SKOV3ip

158 ± 3 nM

n.a.

133 ± 4 nM

120 ± 4 nM

131 ± 3 nM

  1. Abbreviation: n.a. not available
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BMC Cancer

ISSN: 1471-2407

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