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Fig. 2 | BMC Cancer

Fig. 2

From: Knockdown long non-coding RNA ANRIL inhibits proliferation, migration and invasion of HepG2 cells by down-regulation of miR-191

Fig. 2

Knockdown of ANRIL functions in HepG2 cells migration and invasion. HepG2 cells were transfected with the expression vectors of sh-ANRIL#1 and sh-ANRIL#2 to knockdown ANRIL expression. a Transwell assay was performed to analyze cell migration in these transfected cells. b and c Western blot assay was used for examining MMP-2 and MMP-9 protein levels in these transfected cells. d Cell invasion and (e and f) the protein level of Vimentin were determined by Transwell and western blot, respectively. ANRIL: CDKN2B antisense RNA 1; MMP-2/− 9: matrix metalloproteinase-2/− 9; *P < 0.05; **P < 0.01

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