Fig. 2
CD49f is reduced by I2 treatment in HeLa and SiHa monolayers and spheres cells. Monolayer cultures of HeLa and SiHa cells were treated with 200 μM (I2) for 24 h (tinted with line), without treatment (black line), isotype (long dashes) (a and d). Sphere cultures of HeLa and SiHa cells were treated with 200 μM of (I2) for 24 h (tinted grey with line), without treatment (black line), isotype (long dashes) (b and e). CD49f was analyzed by flow cytometry. (a, b, d, e). Data are expressed as mean ± SD (n = 3 independent assays), and the asterisk indicates a significant difference with respect to the control (**P < 0.01, ***P < 0.001) (c and f)