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Table 1 The characteristic differences in the SPCRC

From: Second primary colorectal cancer after the initial primary colorectal cancer

Site group RCC LCC P value Rectal cancer
Number 2144 (43.1%) 1262 (25.4%)   1430 (28.7%)
Mean Age development of 2nd cancer (years) 76.0 74.0 0.146 70.0
Sex    0.113  
 Male 1017 (48.1%) 689 (54.6%)   813 (56.9%)
 Female 1097 (51.9%) 573 (45.4%)   617 (43.1%)
Race
 Black 236 (11.2%) 147 (11.6%)   190 (13.3%)
 White 1563 (73.9%) 873 (69.2%)   882 (61.7%)
 Hispanic/Latino 141 (6.7%) 115 (9.1%)   172 (12.0%)
 Asian or Pacific Islander and others 173 (8.2%) 126 (10.0%)   182 (12.7%)
 Unknown 1 (0.1%) 1 (0.1%)   4 (0.3%)
SEER staging
 Localized 1066 (50.%) 558 (44.2%) 0.061 660 (46.2%)
 Regional 670 (31.7%) 373 (29.6%)   341 (23.8%)
 Distant 245 (11.6%) 218 (17.3%)   218 (15.2%)
 Unknown 133 (6.3%) 113 (9.0%)   211 (14.8%)
Surgery
 No 219 (10.4%) 180 (14.3%)   405 (28.3%)
 Yes 1892 (89.5%) 1079 (85.5%)   1018 (71.2%)
 Unknown     7 (0.5%)
Pathology grade    0.312  
 Well differentiated 200 (9.5%) 127 (10.1%)   115 (8.0%)
 Moderately differentiated 1200 (56.8%) 749 (59.4%)   769 (53.8%)
 Poorly differentiated 422 (20.0%) 169 (13.4%)   172 (12.0%)
 Undifferentiated 27 (1.3%) 13 (1.0%)   11 (0.8%)
Unknown 265 (12.5%) 204 (16.2%)   363 (25.4%)
Calendar year
 1992–2002 801 (37.9%) 490 (38.8%)   460 (32.2%)
 2003–2012 1313 (62.1%) 772 (61.2%)   970 (67.8%)
Median time to secondary cancer (months) 38.0 28.0   31.0
  1. Abbreviations: SPCRC, secondary primary colorectal cancer; RCC, right-sided colon cancer; LCC, left-sided colon cancer. The P values are the difference of the SPCRC between RCC and the LCC