Table 1 The characteristic differences in the SPCRC
From: Second primary colorectal cancer after the initial primary colorectal cancer
Site group | RCC | LCC | P value | Rectal cancer |
|---|---|---|---|---|
Number | 2144 (43.1%) | 1262 (25.4%) | 1430 (28.7%) | |
Mean Age development of 2nd cancer (years) | 76.0 | 74.0 | 0.146 | 70.0 |
Sex | 0.113 | |||
Male | 1017 (48.1%) | 689 (54.6%) | 813 (56.9%) | |
Female | 1097 (51.9%) | 573 (45.4%) | 617 (43.1%) | |
Race | ||||
Black | 236 (11.2%) | 147 (11.6%) | 190 (13.3%) | |
White | 1563 (73.9%) | 873 (69.2%) | 882 (61.7%) | |
Hispanic/Latino | 141 (6.7%) | 115 (9.1%) | 172 (12.0%) | |
Asian or Pacific Islander and others | 173 (8.2%) | 126 (10.0%) | 182 (12.7%) | |
Unknown | 1 (0.1%) | 1 (0.1%) | 4 (0.3%) | |
SEER staging | ||||
Localized | 1066 (50.%) | 558 (44.2%) | 0.061 | 660 (46.2%) |
Regional | 670 (31.7%) | 373 (29.6%) | 341 (23.8%) | |
Distant | 245 (11.6%) | 218 (17.3%) | 218 (15.2%) | |
Unknown | 133 (6.3%) | 113 (9.0%) | 211 (14.8%) | |
Surgery | ||||
No | 219 (10.4%) | 180 (14.3%) | 405 (28.3%) | |
Yes | 1892 (89.5%) | 1079 (85.5%) | 1018 (71.2%) | |
Unknown | 7 (0.5%) | |||
Pathology grade | 0.312 | |||
Well differentiated | 200 (9.5%) | 127 (10.1%) | 115 (8.0%) | |
Moderately differentiated | 1200 (56.8%) | 749 (59.4%) | 769 (53.8%) | |
Poorly differentiated | 422 (20.0%) | 169 (13.4%) | 172 (12.0%) | |
Undifferentiated | 27 (1.3%) | 13 (1.0%) | 11 (0.8%) | |
Unknown | 265 (12.5%) | 204 (16.2%) | 363 (25.4%) | |
Calendar year | ||||
1992–2002 | 801 (37.9%) | 490 (38.8%) | 460 (32.2%) | |
2003–2012 | 1313 (62.1%) | 772 (61.2%) | 970 (67.8%) | |
Median time to secondary cancer (months) | 38.0 | 28.0 | 31.0 | |