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Table 2 Univariate and multivariate survival analysis of non-pCR patients

From: Predictive and prognostic value of Matrix metalloproteinase (MMP) - 9 in neoadjuvant chemotherapy for triple-negative breast cancer patients

Factors Disease-free survival
Univariate Multivariate
P P HR (95% CI)
Age
  < 40 vs. 40–60 vs. ≥ 60 0.062
Menopausal status
 Pre vs. Post 0.150
Initial tumor status
 T2 vs. T3 vs. T4 0.104
Residual tumor size
  ≤ 2 cm vs. 2-5 cm vs. > 5 cm < 0.001 NS
Residual involved nodes
 0 vs. 1–3 vs. ≥4 < 0.001 < 0.001 1.000
   1.409 (0.604–3.289)
   4.124 (1.948–8.732)
Vascular invasion
 Negative vs. Positive 0.035 NS
Grade
 I - II vs. III 0.322
Ki-67
  < 20% vs. ≥ 20% 0.001 0.018 1.909 (1.117–3.262)
sMMP-9 at baseline
 Linear 0.226  
sMMP-9 at surgery
 Linear 0.008 NS
sMMP-9 change
 Linear 0.019 NS
hMMP-9 in residual tumor
 - vs. + vs. ++ < 0.001 0.004 1.000
   2.637 (1.341–5.183)
   2.832 (1.348–5.950)