Table 1 Clinic-pathologic and biologic data of the TNBC patients according to mutational status of PIK3CA
From: Detection of PIK3/AKT pathway in Moroccan population with triple negative breast cancer
| Â | Variables | Overall | PIK3CA wild type | PIK3CA mutated | P-value | |||
|---|---|---|---|---|---|---|---|---|
effective | % | effective | % | effective | % | |||
Age range | < 40 | 11 | 28.2 | 9 | 23.07 | 2 | 5.1 | 0.542 |
> 40 | 28 | 71.7 | 25 | 64.1 | 3 | 7.6 | ||
Localization | Left breast | 30 | 76.9 | 25 | 64.1 | 5 | 12.8 | 0.09 |
Right breast | 9 | 23.0 | 9 | 23.1 | 0 | 0 | ||
Histopathologic type | Ductal carcinoma invasive | 33 | 84.6 | 29 | 74.3 | 4 | 10.2 | 0.729 |
Lobular carcinoma invasive | 6 | 15.3 | 5 | 12.8 | 1 | 2.5 | ||
Grade SBR | II | 12 | 30.7 | 10 | 25.6 | 2 | 5.1 | 0.639 |
III | 27 | 69.2 | 24 | 61.5 | 3 | 7.6 | ||
Ki67 | < 20% | 0 | 0 | 0 | 0 | 0 | 0 | 0.254 |
20–50% | 8 | 20.5 | 6 | 15.3 | 2 | 5.1 | ||
> 50% | 31 | 79.4 | 28 | 71.7 | 6 | 15.3 | ||