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Table 4 Results of multivariate negative binomial modelsa

From: Rigor prophylaxis in stage IV melanoma and renal cell carcinoma patients treated with high dose IL-2

  IRR 95% CI Upper 95% CI Lower p-value
Fever 0.59 0.28 1.24 0.163
Hypotension 0.93 0.43 2.03 0.864
Renal insufficiency 1.10 0.52 2.32 0.807
Rigors via all PRN meds 0.92 0.67 1.26 0.604
Rigors via opioid PRN med 0.90 0.65 1.26 0.554
  1. aAdjusted for age at IL2, IL2 dose, race, gender, previous treatment, malignancy, and additional tramadol
  2. bIncidence Rate ratio
  3. cRigor severity/frequency tabulated via proxy PRN medication of opioids, benzodiazepines, and antihistamines
  4. dRigors severity/frequency tabulated via proxy PRN opioid medications only