EXclusion of non-Involved uterus from the Target Volume (EXIT-trial): an individualized treatment for locally advanced cervical cancer using modern radiotherapy and imaging techniques

Table 1 MRI scan sequences

Timing MRI	Scan Sequence & used MRI device
Standard MRI before, during and 2–3 weeks after CRT	5 mm sagittal T2 Haste, 5 mm sagittal T2 TSE, 4 mm axial T2 TSE, 5 mm axial T1 GE, 4 mm axial DWI (b-values 0, 250, 500 and 1000 with calculated b 1400)
Standard MRI before, during and 2–3 weeks after CRT	at 1.5 Tesla MRI scanner (Siemens Aera, Erlangen, Germany)
Supplemental MRI at the end of treatment and pre-HRT	5 mm sagittal T2 Haste, 5 mm sagittal T2 TSE, 4 mm axial T2 TSE, 5 mm axial T1 GE, 4 mm axial DWI (b-values 50, 400 and 800 with calculated b 1400)
Supplemental MRI at the end of treatment and pre-HRT	at 3.0 Tesla MRI scanner (Siemens Trio or Prisma Fit, Erlangen, Germany)
Hysterectomyspecimen	1 mm coronal T2 Space with 1 mm sagittal and axial reconstructions, 4 mm axial DW (b-values 50, 250,500,750,1000 with calculated b 1400)
Hysterectomyspecimen	at 3.0 Tesla MRI scanner (Siemens Trio or Prisma Fit, Erlangen, Germany)

MRI magnetic resonance imaging, mm millimeter, TSE Turbo Spin Echo, GE Gradient Echo, DWI diffusion weighted imaging

ISSN: 1471-2407