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Table 3 Univariate analyses and multivariate analyses of distant metastasis

From: Nomograms for predicting risk of locoregional recurrence and distant metastases for esophageal cancer patients after radical esophagectomy

  Univariate Multivariate
Variable HR 95%CI P HR 95%CI P
Sex 0.713 0.454–1.119 0.142
Age 0.985 0.970–1.001 0.064
Tumor length 1.129 1.054–1.210 0.001 1.089 0.966–1.228 0.162
Tumor width 1.136 1.034–1.248 0.008 0.949 0.820–1.097 0.477
Tumor site 1.164 0.938–1.446 0.168
Pathological type 1.058 0.684–1.636 0.801
Differentiation 2.354 1.911–2.901 < 0.001 1.831 1.461–2.296 < 0.001
T-staging 1.606 1.311–1.968 < 0.001 1.136 0.897–1.438 0.289
N-staging 1.934 1.720–2.176 < 0.001 1.558 1.366–1.778 < 0.001
LVSI 2.515 1.874–3.375 < 0.001 1.416 1.037–1.935 0.029
PNI 2.774 2.039–3.774 < 0.001 1.598 1.153–2.214 0.005
Adjuvant chemotherapy 2.274 1.731–2.998 < 0.001 1.341 0.997–1.803 0.052
  1. LVSI lymph vascular space invasion, PNI perineural invasion