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Table 2 Association between H19 SNPs and risks of lung adenocarcinoma and squamous cell lung cancer

From: Polymorphisms in the H19 gene and the risk of lung Cancer among female never smokers in Shenyang, China

H19   Controls (%) Lung Adenocarcinoma Squamous cell lung cancer
Cases (%) OR (95% CI) P value OR (95% CI)* P value Cases (%) OR (95% CI) P value OR (95% CI)* P value
rs217727 CC 165(41.8) 141(38.0) 1.00(ref)   1.00(ref)   35(36.5) 1.00(ref)   1.00(ref)  
CT 172(43.5) 169(45.6) 1.150(0.844–1.566) 0.376 1.152(0.846–1.570) 0.369 45(46.9) 1.233(0.755–2.015) 0.402 1.236(0.756–2.022) 0.399
TT 58(14.7) 61(16.4) 1.231(0.805–1.881) 0.337 1.231(0.806–1.881) 0.337 16(16.7) 1.300(0.670–2.523) 0.437 1.315(0.676–2.556) 0.420
CT + TT vs CC    1.170(0.876–1.563) 0.288 1.172(0.877–1.566) 0.283   1.250(0.788–1.983) 0.342 1.256(0.791–1.994) 0.335
TT vs CT + CC    1.143(0.773–1.691) 0.502 1.142(0.773–1.689) 0.505   1.162(0.635–2.128) 0.626 1.173(0.640–2.153) 0.605
C allele 502(63.5) 451(60.8) 1.00(ref)     115(59.9) 1.00(ref)    
T allele 288(36.5) 291(39.2) 1.125(0.915–1.383) 0.265    77(3.6) 1.167(0.845–1.612) 0.384   
rs2107425 CC 140(35.4) 111(29.9) 1.00(ref)   1.00(ref)   27(28.1) 1.00(ref)   1.00(ref)  
CT 185(46.8) 171(46.1) 1.166(0.843–1.613) 0.354 1.166(0.843–1.613) 0.354 43(44.8) 1.205(0.710–2.045) 0.489 1.183(0.696–2.011) 0.536
TT 70(17.7) 89(24.0) 1.604(1.075–2.393) 0.021 1.602(1.074–2.390) 0.021 26(27.1) 1.926(1.046–3.545) 0.035 1.935(1.049–3.570) 0.035
CT + TT vs CC    1.286(0.950–1.741) 0.104 1.286(0.949–1.741) 0.104   1.403(0.859–2.291) 0.176 1.387(0.848–2.268) 0.192
CC vs CT + TT    1.465(1.031–2.082) 0.033 1.464(1.030–2.080) 0.034   1.724(1.026–2.898) 0.040 1.752(1.040–2.952) 0.035
C allele 465(58.9) 393(53.0) 1.00(ref)     97(50.5) 1.00(ref)    
T allele 325(41.1) 349(47.0) 1.271(1.038–1.555) 0.020    95(49.5) 1.401(1.021–1.923) 0.036   
rs2735469 CC 359(90.9) 340(91.6) 1.00(ref)   1.00(ref)   89(92.7) 1.00(ref)   1.00(ref)  
CT 36(9.1) 29(7.8) 0.851(0.510–1.418) 0.535 0.851(0.510–1.418) 0.535 6(6.3) 0.672(0.275–1.645) 0.384 0.662(0.270–1.624) 0.368
TT 0(0) 2(0.5) # # # # 1(1.0) # # # #
CT + TT vs CC    0.909(0.550–1.503) 0.711 0.910(0.550–1.504) 0.712   0.784(0.338–1.821) 0.572 0.775(0.333–1.803) 0.554
TT vs CC + CT    # # # #   # # # #
C allele 754(95.4) 709(95.6) 1.00(ref)     184(95.8) 1.00(ref)    
T allele 36(4.6) 33(4.4) 0.975(0.601–1.581) 0.918    8(4.2) 0.911(0.416–1.992) 0.815   
rs17658052 GG 371(93.9) 343(92.4) 1.00(ref)   1.00(ref)   82(85.4) 1.00(ref)   1.00(ref)  
AG 24(6.1) 27(7.3) 1.217(0.689–2.150) 0.499 1.212(0.685–2.142) 0.509 13(13.5) 2.451(1.198–5.015) 0.014 2.411(1.175–4.946) 0.016
AA 0(0.0) 1(0.3) # # # # 1(1.0) # # # #
AG + AA vs GG    1.262(0.717–2.219) 0.419 1.256(0.714–2.211) 0.429   2.639(1.309–5.321) 0.007 2.587(1.279–5.229) 0.008
AA vs GG + AG    # # # #   # # # #
G allele 766(96.9) 713(96.1) 1.00(ref)    0.410 177(92.2) 1.00(ref)    
A allele 24(3.0) 29(3.9) 1.298(0.749–2.251) 0.352    15(7.8) 2.705(1.390–5.262) 0.002   
  1. *: adjusted by age
  2. #: could not be calculated