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Table 4 The risk estimation of analysed variables and clinical status for histological grade 3 in breast cancer patients (logistic regression adjusted for age)

From: Decreased methylation in the SNAI2 and ADAM23 genes associated with de-differentiation and haematogenous dissemination in breast cancers

  Variables P value OR 95% CI
Grade 3 ↑ Methylation of SNAI2 in PT 0.038 0.61 0.39–0.97
  Ki-67 proliferation index > 20% 0.002 17.34 2.89–103.88
  1. −2 Log likelihood = 31.62; R2(Cox and Snell) = 0.43; R2(Nagelkerke) = 0.60
  2. Abbreviations: PT primary tumour, OR odds ratio, CI confidence interval, ↑ continuous variable. Age and DNA methylation of EMT related genes, hormone receptor and HER2 status, histological type and Ki-67 proliferative index were analysed as independent variables, significant results are shown in the table