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Table 1 Patient characteristics

From: Overexpression of the MRE11-RAD50-NBS1 (MRN) complex in rectal cancer correlates with poor response to neoadjuvant radiotherapy and prognosis

  All Patients
n (%)
Preoperative Radiotherapy Group
Total, n 265 55
Age (median) 71 66
Sex
 Male 176 (66.4) 37 (67.3)
 Female 89 (33.6) 18 (32.7)
Tumor stage
 T1–2 87/260 (33.4) 17/55 (30.9)
 T3–4 173/260 (66.6) 38/55 (69.1)
Node stage
 N0 140/259 (54.1) 29/55 (52.7)
 N1–2 119/259 (45.9) 26/55 (47.3)
Metastasis stage
 M0 223/240 (92.9) 53/54 (98.1)
 M1 17/240 (7.1) 1/54 (1.9)
Grade
 1–2 245/265 (92.5) 51/55 (92.7)
 3 20/265 (7.5) 4/55 (7.3)
Vascular invasion
 Absent 201/263 (76.4) 47/55 (85.5)
 Present 62/263 (23.6) 8/55 (14.5)
Perineural invasion
 Absent 220/263 (83.7) 41/55 (74.5)
 Present 43/263 (16.3) 14/55 (25.5)
Radiotherapy
 Total 77/246 (31.3)
 Neoadjuvant 55/77 (71.4)
 Adjuvant 22/77 (28.6) 0/55 (0)
Recurrence
 Absent 131/213 (61.5) 25/46 (54.3)
 Present 82/213 (28.5) 21/46 (45.7)
Tumor regression grade
 0–1 (good response) 6/55 (10.9)
 2–3 (poor response) 49/55 (89.1)