Table 1 Patient characteristics
| Â | All Patients n (%) | Preoperative Radiotherapy Group |
|---|---|---|
Total, n | 265 | 55 |
Age (median) | 71 | 66 |
Sex | ||
 Male | 176 (66.4) | 37 (67.3) |
 Female | 89 (33.6) | 18 (32.7) |
Tumor stage | ||
 T1–2 | 87/260 (33.4) | 17/55 (30.9) |
 T3–4 | 173/260 (66.6) | 38/55 (69.1) |
Node stage | ||
 N0 | 140/259 (54.1) | 29/55 (52.7) |
 N1–2 | 119/259 (45.9) | 26/55 (47.3) |
Metastasis stage | ||
 M0 | 223/240 (92.9) | 53/54 (98.1) |
 M1 | 17/240 (7.1) | 1/54 (1.9) |
Grade | ||
 1–2 | 245/265 (92.5) | 51/55 (92.7) |
 3 | 20/265 (7.5) | 4/55 (7.3) |
Vascular invasion | ||
 Absent | 201/263 (76.4) | 47/55 (85.5) |
 Present | 62/263 (23.6) | 8/55 (14.5) |
Perineural invasion | ||
 Absent | 220/263 (83.7) | 41/55 (74.5) |
 Present | 43/263 (16.3) | 14/55 (25.5) |
Radiotherapy | ||
 Total | 77/246 (31.3) | – |
 Neoadjuvant | 55/77 (71.4) | – |
 Adjuvant | 22/77 (28.6) | 0/55 (0) |
Recurrence | ||
 Absent | 131/213 (61.5) | 25/46 (54.3) |
 Present | 82/213 (28.5) | 21/46 (45.7) |
Tumor regression grade | ||
 0–1 (good response) | – | 6/55 (10.9) |
 2–3 (poor response) | – | 49/55 (89.1) |