Fig. 1

ECM related molecules are increased in CAF and selectively released in their conditioned medium: a Western Blot analysis of whole lysates of NF and CAF showing the protein levels of the three molecules (COL10A1, SPARC and COL11A1,) in CAF and NF cell cultures. The histograms show relative quantification by densitometric analysis normalized to Vinculin. b Western Blot analysis for the presence of the proteins COL10A1, SPARC and COL11A1 released in the CM of CAF or NF. The histograms show the densitometric analysis (in arbitrary Units) after normalization with respect to total number of cells. The difference was considered significant at p-value < 0.05