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Table 3 Multivariate model predicting total fertility-related distress

From: Determinants of fertility issues experienced by young women diagnosed with breast or gynaecological cancer – a quantitative, cross-cultural study

  B SE B β p
Step 1 – control variables
 Constant 25.49 10.37   ≤0.05
 Age at diagnosis −0.45 0.25 −0.14 n.s.
 Country of origin (Britain vs Poland) 12.45 3.67 0.24 < 0.01
 Type of cancer (gynaecological vs breast) 3.14 5.01 0.059 n.s.
 Type of treatment (sterile vs uncertain fertility) −9.62 4.16 − 0.22 ≤0.05
 Recruitment site (other vs online) −10.42 3.20 −0.24 < 0.01
 Childbearing status (no vs yes) −3.24 2.90 −0.075 n.s.
 Negative affect 1.06 0.153 0.461 < 0.01
Step 2 – desire to have children
 Constant 3.61 11.71   n.s.
 Age at diagnosis −0.17 0.25 −0.053 n.s.
 Country of origin (Britain vs Poland) 13.28 3.53 0.271 < 0.01
 Type of cancer (gynaecological vs breast) 2.32 4.82 0.044 n.s.
 Type of treatment (sterile vs uncertain fertility) −8.18 4.01 −0.184 ≤0.05
 Recruitment site (other vs online) −9.27 3.09 −0.214 ≤0.05
 Childbearing status (no vs yes) −0.48 2.89 −0.011 n.s.
 Negative affect 1.06 0.15 0.46 < 0.01
 Desire to have children 3.43 0.97 0.25 < 0.01
Step 3 – treatment-related regret
 Constant −0.41 11.49   n.s.
 Age at diagnosis −0.14 0.24 −0.04 n.s.
 Country of origin (Britain vs Poland) 13.82 3.44 0.28 < 0.01
 Type of cancer (gynaecological vs breast) 1.45 4.70 0.03 n.s.
 Type of treatment (sterile vs uncertain fertility) −5.76 4.00 −0.13 n.s.
 Recruitment site (other vs online) −8.18 3.03 −0.19 ≤0.05
 Childbearing status (no vs yes) 0.63 2.84 0.02 n.s.
 Negative affect 1.03 0.14 0.45 < 0.01
 Desire to have children 2.97 0.96 0.22 < 0.01
 Treatment related regret (no vs all others) 8.65 3.00 0.19 ≤0.05
Step 4 – culture-related variables
 Constant −6.25 11.80   n.s.
 Age at diagnosis −0.22 0.25 −0.07 n.s.
 Country of origin (Britain vs Poland) 12.21 3.67 0.25 < 0.01
 Type of cancer (gynaecological vs breast) 2.21 4.71 0.04 n.s.
 Type of treatment (sterile vs uncertain fertility) −7.26 4.07 −0.16 n.s.
 Recruitment site (other vs online) −8.31 3.05 −0.19 ≤0.05
 Childbearing status (no vs yes) −0.80 3.07 −0.02 n.s.
 Negative affect 0.94 0.15 0.41 < 0.01
 Desire to have children 2.30 1.02 0.17 ≤0.05
 Treatment related regret (no vs all others) 8.27 3.05 0.18 ≤0.05
 Cultural disapproval of childlessness (no vs all others) 3.85 2.74 0.09 n.s.
 VOC_U 1.50 2.66 0.05 n.s.
 VOC_S −0.99 3.01 −0.03 n.s.
 VOC_P 3.28 2.26 0.12 n.s.
Step 5 – illness perceptions
 Constant −11.68 11.54   n.s.
 Age at diagnosis −0.27 0.24 −0.08 n.s.
 Country of origin (Britain vs Poland) 11.58 3.55 0.24 < 0.01
 Type of cancer (gynaecological vs breast) −0.17 4.61 −0.01 n.s.
 Type of treatment (sterile vs uncertain fertility) −5.49 3.98 −0.12 n.s.
 Recruitment site (other vs online) −6.41 3.01 −0.15 ≤0.05
 Childbearing status (no vs yes) −2.31 3.01 −0.05 n.s.
 Negative affect 0.70 0.16 0.31 < 0.01
 Desire to have children 2.03 0.99 0.15 ≤0.05
 Treatment related regret (no vs all others) 7.27 2.97 0.16 ≤0.05
 Cultural disapproval of childlessness (no vs all others) 2.94 2.66 0.07 n.s.
 VOC_U 1.28 2.57 0.05 n.s.
 VOC_S −1.70 2.92 −0.06 n.s.
 VOC_P 4.10 2.20 0.15 n.s.
 Brief-IPQ total 0.35 0.11 0.23 < 0.01
  1. Step 1: R2 = 0.466, adjusted R2 = 0.438, F(7, 134) = 16.69, p < 0.01
  2. Step 2: R2 = 0.512, adjusted R2 = 0.482, F(1, 133) = 12.55, p < 0.01, Δ R2 = 0.046
  3. Step 3: R2 = 0.541, adjusted R2 = 0.509, F(1, 132) = 8.31, p < 0.01, Δ R2 = 0.029
  4. Step 4: R2 = 0.561, adjusted R2 = 0.516, F(4, 128) = 1.48, p = n.s., Δ R2 = 0.020
  5. Step 5: R2 = 0.593, adjusted R2 = 0.548, F(1, 127) = 9.99, p < 0.01, Δ R2 = 0.032