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Fig. 6 | BMC Cancer

Fig. 6

From: Knockdown of TIPE2 increases the proliferation in lipopolysaccharide-stimulated gastric cancer cells

Fig. 6

LPS stimulated TIPE2 knockdown cells show increased levels of pAKT and pIkBa as well as CyclinD3 and CDK4. a and b AKT, IκBα and ERK phosphorylation levels were analyzed in the stable TIPE2 knockdown SGC7901 and BGC823 cells. AKT and IκBα phosphorylation was up-regulated in the TIPE2 knockdown SGC7901 and BGC823 cells, while no significant differences in ERK phosphorylation were observed. The cell cycle related proteins were examined. CDK4 and CyclinD3 levels were significantly upregulated in TIPE2 knockdown SGC7901 and BGC823 cells compared with control cells. c The histograms of quantitative analysis. All of the experiments were performed in triplicate. *P < 0.05

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