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Table 2 % cancers of the vulva treated by surgery (and odds ratios for surgery) as part of the primary course of treatment; Australian major public hospitals, 1984–2016 diagnoses

From: Using hospital registries in Australia to extend data availability on vulval cancer treatment and survival

Number of cases

Surgery (%)

p value*

Mann-Whitney or Fisher Exact Test

Odds ratiosa - adjusted (95% CIs)

All (n = 383)

93.7

Age at diagnosis (yrs.):

 < 50 (n = 56)

98.2

MW p = 0.452

1.00

 50–69 (n = 100)

91.0

0.28 (0.03, 2.58)

 70–79 (n = 113)

95.6

0.64 (0.06, 6.38)

 80+ (n = 114)

92.1

0.30 (0.03, 2.77)

FIGO stage:

 I (n = 167)

98.2

MW p = < 0.001 (excluding UK)

1.00

 II (n = 103)

97.1

0.70 (0.13, 3.87)

 III (n = 68)

83.8

0.13 (0.03, 0.53)

 IV (n = 29)

79.3

0.11 (0.02, 0.53)

 (Unknown (n = 16))

(93.8)

(0.76 (0.07, 8.87))

Differentiation:

 Well (n = 102)

99.0

MW p = 0.002 (excluding UK)

1.00

 Moderate (n = 136)

94.1

0.25 (0.03, 2.28)

 Poorly/undifferentiated (n = 75)

90.7

0.22 (0.02, 0.53)

 (Unknown (n = 70)

(88.6)

(0.13 (0.01, 1.28))

Histology:

 Squamous cell carcinoma (n = 341)

94.4

FET p = 0.165

1.00

 Other (n = 42)

88.1

0.59 (0.16, 2.13)

Socioeconomic (SEIFA):

 Low (n = 138)

96.4

MW p = 0.021

1.00

 Low/med (n = 75)

94.7

0.58 (0.13, 2.64)

 Med/high (n = 77)

94.8

0.69 (0.15, 3.05)

 High (n = 93)

88.2

0.33 (0.10, 1.13)

Geographic remoteness:

 Low (n = 314)

93.6

MW p = 0.757

1.00

 Moderate (n = 45)

91.1

0.35 (0.09, 1.40)

 High (n = 24)

100.0

0.00 (0.00, 3.26)

Diagnostic period (calendar years.):

 1984–99 (n = 199)

95.5

FET p = 0.205

1.00

 2000–16 (n = 184)

91.8

0.79 (0.28, 2.20)

  1. *Derived from Mann-Whitney U Test (ordinal) or Fisher Exact Test (binary)
  2. aDerived from multiple logistic regression, adjusting for other variables in the Table