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Table 2 Multivariate cox regression analysis for overall survival and recurrence-free survival in ccRCC patientsá…Ÿ

From: Low level of isocitrate dehydrogenase 1 predicts unfavorable postoperative outcomes in patients with clear cell renal cell carcinoma

Variables

Overall survival

Recurrence-free survival

HR

(95% CI)

p*

HR

(95% CI)

p*

IDH1 in cancer tissues

 Low

1

  

1

  

 High

0.500

0.253–0.987

0.046*

0.463

0.233–0.922

0.028*

TNM stage

  I

1

  

1

  

 II + III + IV

3.866

1.185–12.610

0.025*

6.453

1.645–25.309

0.007*

T stage

 T1 + T2

1

  

1

  

 T3 + T4

2.991

1.197–7.473

0.019*

2.076

0.901–4.785

0.086

N stage

 N0

1

  

1

  

 N1

3.884

1.418–10.640

0.008*

3.319

1.253–8.792

0.016*

Fuhrman grade

 I + II

1

  

1

  

 III + IV

2.255

1.314–3.869

0.003*

2.069

1.203–3.557

0.009*

Tumor size(cm)

  ≤ 4

1

  

1

  

  > 4

3.261

1.584–6.712

0.001*

3.482

1.658–7.313

0.001*

  1. HR hazard ratio, 95% CI 95% confidence interval, *p < 0.05 was considered statistically significant