BMC Cancer

Table 1 Association of IDH1 expression with clinicopathological characteristics in ccRCC patients

From: Low level of isocitrate dehydrogenase 1 predicts unfavorable postoperative outcomes in patients with clear cell renal cell carcinoma

Characteristics	Patients		IDH1 expression
Characteristics	n	%	Low	High	p-value
All patients	358	100	264	94
Gender
Male	254	70.9	189	65	0.654^a
Female	104	29.1	75	29
Age(years)
≤ 55	178	49.7	125	53	0.132^a
> 55	180	50.3	139	41
TNM stage
I	286	79.9	208	78	0.384^a
II + III + IV	72	20.1	56	16
T stage
T1 + T2	344	96.1	253	91	1.000^b
T3 + T4	14	3.9	11	3
N stage
N0	349	97.5	256	93	0.455^b
N1	9	2.5	8	1
M stage
M0	352	983	260	92	0.655^b
M1	6	1.7	4	2
Fuhrman grade
I + II	297	83.0	212	85	0.025^a*
III + IV	61	17.0	52	9
Tumor size(cm)
≤ 5	186	52.0	134	52	0.447^a
> 5	172	48.0	130	42
Necrosis
Absent	296	82.7	216	80	0.469^a
Present	62	17.3	48	14
SSIGN score
< 4	266	74.3	193	73	0.386^a
≥ 4	92	25.7	71	21

^aChi-square test
^bFisher’s exact test
*p < 0.05 indicates a significant association among the variables

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