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Table 2 Lesion of uncertain malignant potential (B3) on CBN with excision histology outcome for different B3 lesions and associated PPV for breast malignancy

From: Lesions of “uncertain malignant potential” in the breast (B3) identified with mammography screening

Category of B3 diagnosis (CNB) with excision histology (number of cases)

Final excision diagnosis

Benign

Malignant in situ no. (%)

Malignant invasive no. (%)

PPV (%) excision histology

FEA (73)

58

11 (15.1)

4 (5.4)

20,5 (15/73)

ADH (135)

81

32 (23.7)

22 (16.3)

40 (54/135)

Papillary lesion (37)

32

2 (5.4)

3 (8.1)

13.5 (5/37)

Radial scar (24)

20

3 (12.5)

1 (4.1)

16.6 (4/24)

LN (30)

30

0

0

0 (0/30)

Total (299)

221

48 (16.1)

30 (10)

26,1 (78/299)

  1. FEA flat epithelial atypia, ADH atypical ductal hyperplasia, LN lobular neoplasia, CBN core needle biopsy, PPV positive predictive value