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Table 2 Control Sample Results Across Participating Laboratories

From: Simultaneous detection of lung fusions using a multiplex RT-PCR next generation sequencing-based approach: a multi-institutional research study

Laboratory Sample ALK fusion ROS1 fusion RET fusion NTRK1 fusion ALK 3′/5′ imbalance ROS1 3′/5′ imbalance RET 3′/5′ imbalance NTRK 3′/5′ imbalance
INSERM Cell Line RNA cocktaila Detected Detected Detected n/a 0.0044 0.3031 0.0603 n/a
Kinki Cell Line RNA cocktaila Detected Detected Detected n/a 0.0405 0.4648 0.0434 n/a
ARUP Cell Line RNA cocktaila Detected Detected Detected n/a 0.0172 0.6141 0.0421 n/a
ARC-Net Cell Line RNA cocktaila Detected Detected Detected n/a 0.0086 0.3458 0.0353 n/a
Viollier Cell Line RNA cocktaila Detected Detected Detected n/a 0.043 0.3398 0.046 n/a
Radboudumc Cell Line RNA cocktaila Detected Detected Detected n/a 0.0414 0.2502 0.0856 n/a
CROM Cell Line RNA cocktaila Detected Detected Detected n/a 0.012 0.054 0.0813 n/a
IPATIMUP Cell Line RNA cocktaila Detected Detected Detected n/a 0.0238 0.2877 0.0539 n/a
Warwick Cell Line RNA cocktaila Detected Detected Detected n/a 0.0064 0.3 0.055 n/a
Queen’s Cell Line RNA cocktaila Detected Detected Detected n/a 0.0123 0.4158 0.0478 n/a
ARUP FFPE cell block H2228 Detected n/a n/a n/a 0.0312 n/a n/a n/a
ARUP FFPE cell block HCC78 n/a Detected n/a n/a n/a 3.8313 n/a n/a
ARUP FFPE cell block LC-2/ad n/a n/a Detected n/a n/a n/a 0.2521 n/a
Kinki Fresh cells H3122 Detected n/a n/a n/a 0.3165 n/a n/a n/a
ARUP FFPE cell block KM-12 n/a n/a n/a Not covered n/a n/a n/a 0.076
  1. aA mixture of RNA from three cell lines (H2228, HCC78, and LC-2/ad)