Smoking status | 0 (n = 14) | 1 (n = 22) | 2 (n = 30) | 3 (n = 60) | p-value |
---|---|---|---|---|---|
Median age (range) | 63 (44–73) | 64 (46–75) | 63 (42–76) | 64 (46–79) | ** 0.3949 |
Gender | |||||
 Male | 10 | 20 | 25 | 57 | *0.04537 |
 Female | 4 | 2 | 5 | 3 |  |
Location | |||||
 Ce | 1 | 0 | 1 | 0 | *0.02068 |
 Ut | 4 | 3 | 1 | 6 |  |
 Mt | 4 | 6 | 18 | 21 |  |
 Lt | 5 | 13 | 7 | 28 |  |
 Ae | 0 | 0 | 3 | 5 |  |
Histology | |||||
 SCC | 14 | 21 | 28 | 53 | *0.642 |
 Others | 0 | 1 | 2 | 7 |  |
TNMÂ (UICC6th) | |||||
 T1 | 1 | 2 | 0 | 2 | *0.163 |
 T2 | 2 | 2 | 0 | 2 |  |
 T3 | 11 | 18 | 30 | 54 |  |
 T4 | 0 | 0 | 0 | 2 |  |
 N0 | 4 | 5 | 11 | 10 | *0.1923 |
 N1 | 10 | 17 | 19 | 50 |  |
 M0 | 11 | 18 | 24 | 51 | *0.7328 |
 M1a | 2 | 2 | 1 | 4 |  |
 M1b | 1 | 2 | 5 | 5 |  |
Adjuvant | |||||
 NAC | 6 | 11 | 17 | 31 | *0.8629 |
 No NAC | 8 | 11 | 13 | 29 |  |
HER2 | |||||
 > median | 4 | 12 | 17 | 31 | *0.357 |
 < median | 10 | 10 | 13 | 29 |  |
MET | |||||
 > median | 5 | 13 | 16 | 33 | *0.5689 |
 < median | 9 | 9 | 14 | 27 |  |
EGFR | |||||
 > median | 6 | 10 | 14 | 32 | *0.8578 |
 < median | 8 | 12 | 16 | 28 |  |
ALK | |||||
 > median | 6 | 14 | 13 | 29 | *0.4895 |
 < median | 8 | 8 | 17 | 31 |  |
HGF | |||||
 > median | 4 | 9 | 14 | 34 | *0.2289 |
 < median | 10 | 13 | 16 | 26 |  |
TP53 | |||||
 Wild type | 7 | 8 | 7 | 20 | *0.372 |
 Mutation | 7 | 14 | 23 | 40 |  |
APC | |||||
 Wild type | 14 | 20 | 26 | 53 | *0.6702 |
 Mutation | 0 | 2 | 4 | 7 |  |
PIK3CA | |||||
 Wild type | 14 | 16 | 28 | 54 | *0.06858 |
 Mutation | 0 | 6 | 2 | 6 |  |
FBXW7 | |||||
 Wild type | 14 | 19 | 27 | 56 | *0.516 |
 Mutation | 0 | 3 | 3 | 4 |  |
BRAF | |||||
 Wild type | 14 | 20 | 28 | 55 | *0.8769 |
 Mutation | 0 | 2 | 2 | 5 |  |