Hornerin promotes tumor progression and is associated with poor prognosis in hepatocellular carcinoma

BMC Cancer

Table 1 Relationship between the expression of HRNR and clinicopathological characteristics

Category	Subcategory	Cases	HRNR expression		P value
Category	Subcategory	Cases	Low (n = 114)	High (n = 157)	P value
Gender	male	240	98	142
Gender	female	31	16	15	0.826
Age (years)	≤ 50	131	56	75
Age (years)	> 50	140	58	82	0.253
HCC family history	Yes	18	8	10
HCC family history	No	253	106	147	0.665
HBsAg	negative	32	14	18
HBsAg	positive	239	100	139	0.837
Child-pugh stage	A	269	113	156
Child-pugh stage	B	2	1	1	0.820
AFP(ng/ml)	< 20	67	22	45
AFP(ng/ml)	≥20	204	92	112	0.078
Edmonson Grading	I-II	212	96	116
Edmonson Grading	III-IV	59	18	41	0.042
Tumor Size (cm)	≤ 5	96	47	49
Tumor Size (cm)	> 5	175	67	108	0.089
Liver Cirrhosis	absent	55	27	28
Liver Cirrhosis	present	216	87	129	0.237
Capsulation	capsulated	171	76	95
Capsulation	non-caspulated	100	38	62	0.300
Tumor Number	single	185	85	100
Tumor Number	multiple	86	29	57	0.058
Vascular Invasion	Yes	56	16	40
Vascular Invasion	No	215	98	117	0.022
TNM Stage	I-II	152	80	72
TNM Stage	III-IV	119	34	85	< 0.001

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