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Table 1 Association between gastrin levels and clinicopathological variables of 93 breast cancer cases

From: Low serum gastrin associated with ER+ breast cancer development via inactivation of CCKBR/ERK/P65 signaling

Clinicopathological parameters

Na

Gastrin levels (pg/ml)

χ2

P Value

<149b

≥149

All

93

75

18

  

Age(year)

   

0.155

0.694

 <45

40

33

7

  

  ≥ 45

53

42

11

  

Grade(WHO)

   

2.538

0.281

 I

11

8

3

  

 II

70

59

11

  

 III

12

8

4

  

Histopathological type

   

14.530

0.000*

 ER+

69

62

7

  

 ER−

24

13

11

  

Tumor size (cm)

   

11.627

0.001*

 <2

16

8

8

  

  ≥ 2

77

67

10

  

Local lymph node metastasis

   

0.000

0.986

 yes

36

29

7

  

 no

57

46

11

  
  1. aNumber of cases in each group
  2. bThe mean value of serum gastrin level of normal persons
  3. *Statistically significant (P < 0.05)