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No size limit
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Maximum CRLM size ≤3 cm
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Aiming at negative (R0) margins
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Aiming at a tumour free margin of > 10 mm
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Leave sufficient FLR (> 20% normal functioning liver parenchyma; > 30% post-chemotherapy)
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Leave sufficient FLR (> 20% normal functioning liver parenchyma; > 30% post-chemotherapy)
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Portal vein embolization of the (most) affected liver lobe may be considered for patients with insufficient FLR
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To preserve the major bile ducts (common, right and left hepatic duct) a minimum distance (lesion to major bile duct) of 15 mm is required
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At least one of three hepatic veins should be preserved and both the portal venous and hepatic arterial blood flow in the future liver remnant should be remain unharmed
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Radical ablation(s) with or without surgical resections for additional unablatable lesions
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Approachable surgical field, without extensive scar formation, major surgical adhesions and/or intestinal herniations (risk of major morbidity estimated > 20%; risk of mortality estimated > 5%)
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To avoid collateral damage to the intestines a minimum distance to the stomach, small bowel and colon of 15 mm should be pursued in open procedures and respected in percutaneous procedures; Pneumo- or hydrodissections to shift bowels are allowed
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Maximum total number of CRLM 10
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Maximum total number of CRLM 10
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