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Table 2 Quantification of SPLs (VIP > 1) in A549 and A549T

From: LC-MS based sphingolipidomic study on A549 human lung adenocarcinoma cell line and its taxol-resistant strain

SPLs Content (pmol/5*105 cells) ChangeA549T vs A549 p value VIP
A549 (n = 20) A549T (n = 20)
SM (d18:2/20:0) 1.96 ± 0.16 0.53 ± 0.07 < 0.001 1.07408
SM (d18:1/26:1) 19.8 ± 1.22 0.34 ± 0.04 < 0.001 1.08696
SM (d18:1/26:0) 5.67 ± 0.31 0.20 ± 0.02 < 0.001 1.08775
SM (d18:1/25:1) 9.28 ± 0.43 0.45 ± 0.05 < 0.001 1.08860
SM (d18:1/25:0) 4.09 ± 0.23 0.42 ± 0.04 < 0.001 1.08699
SM (d18:1/24:3) 3.34 ± 0.26 0.47 ± 0.07 < 0.001 1.08120
SM (d18:1/24:2) 32.5 ± 1.55 8.99 ± 0.87 < 0.001 1.08501
SM (d18:1/24:1) 542 ± 23.8 37.9 ± 2.59 < 0.001 1.08879
SM (d18:1/24:0) 298 ± 13.0 41.5 ± 3.16 < 0.001 1.08829
SM (d18:1/23:2) 1.12 ± 0.11 0.25 ± 0.04 < 0.001 1.06488
SM (d18:1/23:1) 21.6 ± 1.08 2.58 ± 0.30 < 0.001 1.08745
SM (d18:1/23:0) 26.4 ± 1.26 6.57 ± 0.51 < 0.001 1.08618
SM (d18:1/22:2) 1.25 ± 0.12 0.15 ± 0.02 < 0.001 1.07067
SM (d18:1/22:1) 16.4 ± 0.81 2.07 ± 0.18 < 0.001 1.08760
SM (d18:1/22:0) 142 ± 6.17 26.9 ± 1.78 < 0.001 1.08783
SM (d18:1/21:1) 0.82 ± 0.07 0.15 ± 0.02 < 0.001 1.07308
SM (d18:1/21:0) 4.66 ± 0.25 1.39 ± 0.12 < 0.001 1.08216
SM (d18:1/20:1) 0.87 ± 0.13 0.06 ± 0.00 < 0.001 1.06102
SM (d18:1/20:0) 17.6 ± 0.86 3.08 ± 0.31 < 0.001 1.08689
SM (d18:1/19:0) 1.94 ± 0.20 0.21 ± 0.03 < 0.001 1.07588
SM (d18:1/18:1) 39.0 ± 1.99 8.13 ± 0.58 < 0.001 1.08637
SM (d18:1/18:0) 69.5 ± 2.72 9.07 ± 0.54 < 0.001 1.08896
SM (d18:1/17:0) 14.1 ± 0.72 4.76 ± 0.39 < 0.001 1.08307
SM (d18:1/16:0) 982 ± 38.5 629 ± 23.5 < 0.001 1.06108
SM (d18:1/14:0) 27.3 ± 1.04 17.2 ± 0.65 < 0.001 1.06732
SM (d18:0/24:0) 15.3 ± 0.78 0.11 ± 0.02 < 0.001 1.08843
SM (d18:0/23:0) 2.45 ± 0.15 0.02 ± 0.00 < 0.001 1.08694
SM (d18:0/22:0) 23.3 ± 1.05 0.23 ± 0.04 < 0.001 1.08900
SM (d18:0/20:0) 4.59 ± 0.24 0.08 ± 0.01 < 0.001 1.08808
SM (d18:0/19:0) 0.49 ± 0.07 0.01 ± 0.00 < 0.001 1.05519
SM (d18:0/18:0) 17.0 ± 0.55 0.10 ± 0.03 < 0.001 1.09013
SM (d18:0/17:0) 0.65 ± 0.07 0.06 ± 0.01 < 0.001 1.07030
SM (d18:0/16:0) 545 ± 28.7 12.3 ± 0.94 < 0.001 1.08809
SM (d18:0/15:0) 1.74 ± 0.16 0.10 ± 0.02 < 0.001 1.08041
SM (d18:0/14:0) 5.83 ± 0.40 0.28 ± 0.03 < 0.001 1.08565
Cer (d18:2/24:1) 1.01 ± 0.21 0.03 ± 0.01 < 0.001 1.04397
Cer (d18:1/24:1) 46.1 ± 5.83 3.60 ± 0.44 < 0.001 1.07110
Cer (d18:1/24:0) 42.0 ± 2.08 9.83 ± 0.41 < 0.001 1.08653
Cer (d18:1/23:1) 1.37 ± 0.22 0.06 ± 0.01 < 0.001 1.06057
Cer (d18:1/23:0) 2.54 ± 0.27 0.53 ± 0.09 < 0.001 1.06941
Cer (d18:1/22:1) 1.20 ± 0.27 0.04 ± 0.01 < 0.001 1.03542
Cer (d18:1/22:0) 14.4 ± 0.94 1.90 ± 0.39 < 0.001 1.08443
Cer (d18:1/20:0) 1.69 ± 0.33 0.07 ± 0.02 < 0.001 1.04721
Cer (d18:1/18:1) 20.1 ± 1.33 4.03 ± 0.49 < 0.001 1.08187
Cer (d18:1/18:0) 8.03 ± 0.72 0.26 ± 0.04 < 0.001 1.08142
Cer (d18:1/16:0) 52.0 ± 3.59 10.7 ± 0.98 < 0.001 1.08243
Cer (d18:1/15:0) 3.14 ± 0.46 1.34 ± 0.30 < 0.001 1.00100
Cer (d18:0/24:0) 1.44 ± 0.11 0.34 ± 0.04 < 0.001 1.07587
Cer (d18:0/16:0) 3.46 ± 0.25 0.07 ± 0.01 < 0.001 1.05883
HexCer (d18:1/26:0) 0.41 ± 0.10 0.04 ± 0.02 < 0.001 1.00780
HexCer (d18:1/24:1) 9.25 ± 0.97 0.02 ± 0.00 < 0.001 1.07959
HexCer (d18:1/16:0) 5.06 ± 0.89 21.6 ± 2.10 < 0.001 1.07118
LacCer (d18:1/24:1) 0.22 ± 0.05 19.9 ± 2.17 < 0.001 1.07014
LacCer (d18:1/24:0) 0.37 ± 0.03 56.4 ± 3.16 < 0.001 1.07766
LacCer (d18:1/22:0) 0.06 ± 0.01 21.6 ± 2.85 < 0.001 1.07258
LacCer (d18:1/16:0) 1.15 ± 0.55 115 ± 11.6 < 0.001 1.08013
So (t17:1) 2.21 ± 0.17 0.62 ± 0.08 < 0.001 1.07483