Table 1 Molecular characteristics and drug resistance of cell lines
Cell lines | KRAS | BRAF | p53 | PI3K | Drug resistance |
|---|---|---|---|---|---|
HCT116 | G13D | wt | wt | H1047R | EGFRi |
HCT116-SN6 | G13D | wt | wt | H1047R | SN38/EGFRi |
HCT116-SN50 | G13D | wt | wt | H1047R | SN38/EGFRi |
SW480 | G12 V | wt | R273H/P309S | wt | EGFRi |
LS174T | G12D | wt | wt | H1047R | EGFRi |
HT29 | wt | V600E | R273H | wt | EGFRi |
SW48 | wt | wt | wt | wt | none |