Fig. 3From: Rational development of synergistic combinations of chemotherapy and molecular targeted agents for colorectal cancer treatmentIn vitro testing of the BKM120-MEK162 synergism in HCT116 cell spheroids. (a) Microphotographs of spheroids after 14 days of incubation with BKM120 and MEK162 at the indicated doses. (b) Experimental survival data (top) and synergism (bottom) matricesBack to article page