Fig. 6
From: Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines
NCO-90/141 induce both caspase-dependent and -independent cell death with caspase activities. S1T, MT-2, Jurkat, and HL60 cells were treated with NCO-90 (50 μM) or NCO-141 (S1T and MT-2 cells, 50 μM; Jurkat and HL-60 cells, 100 μM) and Z-VAD-FMK (40 μM) for 72 h. a–c Caspase-positive cells were detected by flow cytometry. Data represent mean percentages ± SD of three independent experiments