Fig. 2
From: Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines
NCO-90/141 reduce cell viability in leukemic cell lines. a SIRT2 protein in leukemic cell lines was analyzed by western blotting. b Cell lines were incubated at 2 × 105 cells/mL in the presence of various concentrations of NCO-90 and NCO-141 for 72 h. The viabilities of the cultured cells were measured by Cell Count Reagent SF. Cells cultured in the absence of each SIRT2 inhibitor were assigned a relative viability of 1. Data represent mean percentages ± SD of three independent experiments. *P < 0.05 vs. 0 μM