Fig. 3
From: Differential expression of Cosmc, T-synthase and mucins in Tn-positive colorectal cancers
Expression of the Tn and Sialyl-Tn (STn) neoantigens in human CRCs. a, representative immunohistochemistry (IHC) of the Tn antigen in 2 cases of matched normal and tumor specimens. b, representative IHC of STn in 2 cases of CRCs. In both a and b, ādistal TMā and āproximal TMā denote transitional mucosa (TM) located far and near to the malignant cells, respectively. Compared to the matched normal sections and ādistal TMā crypts, the āproximal TMā crypts had increased intracellular Tn and STn antigens. All scale bars are 100Ā Ī¼m. c, IHC score (IS) of Tn and STn levels in normal and tumor sections. IS of each staining was plotted with triangle (normal) and square (tumor) shaped boxes respectively. The mean and standard error (SEM) values are indicated by longer lines and shorter lines, respectively. The p-values were generated using Paired sample t test