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Table 1 Receive operating characteristics analysis when using cut-off ≥3.31 ng/μl

From: TRH site-specific methylation in oral and oropharyngeal squamous cell carcinoma

  Comparative data Area Under the ROC Curve (AUC), Standard Error (95% CI) Sensitivity% (95% CI) Specificity% (95% CI) Likelihood ratio
Cohort 1 Oral rinse from oral cancer subjects: Oral rinse from healthy controls 0.90, 0.043 (0.82 to 0.98) 82.61 (61.22 to 95.05) 84.85 (68.10 to 94.89) 5.45
Oral swab from oral cancer subjects: Oral rinse from healthy controls 0.97, 0.02 (0.93 to 1.01) 91.30 (71.96 to 98.93) 84.85 (68.10 to 94.89) 6.03
Cohort 2 Oral rinse from oral cancer subjects: Oral rinse from healthy controls 0.93, 0.03 (0.88 to 0.99) 88.10 (74.37 to 96.02) 92.59 (82.11 to 97.94) 11.89
Oral rinse from oropharyngeal cancer subjects: Oral rinse from healthy controls 0.88, 0.05 (0.77 to 0.98) 82.61 (61.22 to 95.05) 92.59 (82.11 to 97.94) 11.15
Cohort 1 + 2 Oral rinse from oral cancer subjects: Oral rinse from healthy controls 0.93, 0.02 (0.88 to 0.97) 86.15 (75.34 to 93.47) 89.66 (81.27 to 95.16) 8.33
  1. CI confidence interval