Table 1 Receive operating characteristics analysis when using cut-off ≥3.31 ng/μl
From: TRH site-specific methylation in oral and oropharyngeal squamous cell carcinoma
| Â | Comparative data | Area Under the ROC Curve (AUC), Standard Error (95% CI) | Sensitivity% (95% CI) | Specificity% (95% CI) | Likelihood ratio |
|---|---|---|---|---|---|
Cohort 1 | Oral rinse from oral cancer subjects: Oral rinse from healthy controls | 0.90, 0.043 (0.82 to 0.98) | 82.61 (61.22 to 95.05) | 84.85 (68.10 to 94.89) | 5.45 |
Oral swab from oral cancer subjects: Oral rinse from healthy controls | 0.97, 0.02 (0.93 to 1.01) | 91.30 (71.96 to 98.93) | 84.85 (68.10 to 94.89) | 6.03 | |
Cohort 2 | Oral rinse from oral cancer subjects: Oral rinse from healthy controls | 0.93, 0.03 (0.88 to 0.99) | 88.10 (74.37 to 96.02) | 92.59 (82.11 to 97.94) | 11.89 |
Oral rinse from oropharyngeal cancer subjects: Oral rinse from healthy controls | 0.88, 0.05 (0.77 to 0.98) | 82.61 (61.22 to 95.05) | 92.59 (82.11 to 97.94) | 11.15 | |
Cohort 1 + 2 | Oral rinse from oral cancer subjects: Oral rinse from healthy controls | 0.93, 0.02 (0.88 to 0.97) | 86.15 (75.34 to 93.47) | 89.66 (81.27 to 95.16) | 8.33 |