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Table 5 Relative Expression and Survival Correlation of Mismatch Repair Genes

From: Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes

Gene UVM Cluster 1 Above/Below Average (%/%) UVM Cluster 2 Above/Below Average (%/%) UVM Cluster 3 Above/Below Average (%/%) UVM Cluster 4 Above/Below Average (%/%) P Value 1&2 vs 3&4 Fisher’s Exact Two Tailed Total Cases Above Average Total Cases Below Average Kaplan Meier Worse Survival Kaplan Meier Log-rank
n = 15 n = 23 n = 22 n = 20
MLH1 11/4 (73/27) 13/10 (57/43) 7/15 (32/68) 11/9 (55/45) 0.0781 42 38 NA 0.9990
MLH3 6/9 (40/60) 9/14 (39/61) 12/10 (55/45) 16/4 (80/20) 0.0242 43 37 NA 0.3170
MSH2 7/8 (47/53) 12/11 (52/48) 9/13 (41/59) 16/4 (80/20) 0.5004 44 36 NA 0.7404
MSH3 8/7 (53/47) 11/12 (48/52) 9/13 (41/59) 16/4 (80/20) 0.5004 44 36 NA 0.3593
MSH6 4/11 (27/73) 13/10 (57/43) 10/12 (46/54) 16/4 (80/20) 0.0357 43 37 NA 0.7278
PMS1 6/9 (40/60) 9/14 (39/61) 9/13 (41/59) 16/4 (80/20) 0.1165 40 40 NA 0.3997
PMS2 8/7 (53/47) 15/8 (65/35) 11/11 (50/50) 14/6 (70/30) 1.0000 48 32 NA 0.7110
EXO1 8/7 (53/47) 10/13 (43/57) 4/18 (18/82) 13/7 (65/35) 0.6526 35 45 NA 0.4349