Fig. 2
From: Examining transcriptional changes to DNA replication and repair factors over uveal melanoma subtypes
Alterations to the Mini Chromosome Maintenance (MCM) Helicase Complex a RNA- Seq abundance of MCM2 across tumor types, highest to lowest expression UVM (black arrow). b Differential Expression, mRNA expression z-scores (RNA-Seq V2 RSEM) (log2) for MCM2, MCM4, and MCM5, median and SD. Putative copy-number alterations are from GISTIC. c Relative Expression, mRNA Expression z-scores (RNA-Seq RPKM) (log2) organized across UVM clusters 1–4, mean and SEM. d Kaplan Meier Survival Plot, cases “above” (red) “below” average (blue) zero z-score, Log-rank test