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Fig. 3 | BMC Cancer

Fig. 3

From: Aberrant DNA methylation of ADAMTS16 in colorectal and other epithelial cancers

Fig. 3

Comparision of hyper/hypomethylated ADAMTS16 CpGs in colorectal cancer (CRC), lung cancer (LC) and oral squamous-cell carcinoma (SCC) patients. a Six hypermethylated ADAMTS16 CpGs in CRC patients were also hypermethylated in LC and SCC patients. Data represent the methylation (β-value) for individual patients (spots) with the mean ± SEM (red lines). Data were statistically analyzed with Wilcoxon signed-rank test and corrected for multiple testing with Benjamini-Hochberg method (**** P < 0.0001, (n = 117 (CRC), n = 40 (LC), n = 15 (SCC)). ctrl = peri-tumoral non-malignant tissue; canc = cancer tissue; SEM = standard error of mean. b Two hypomethylated ADAMTS16 CpGs in CRC patients are also hypomethylated in LC and SCC patients. Data represent the methylation (β-value) for individual patients (spots) with the mean ± SEM (red lines). Data were statistically analyzed with Wilcoxon signed-rank test and corrected for multiple testing with Benjamini-Hochberg method (**** P < 0.0001, (n = 117 (CRC), n = 40 (LC), n = 15 (SCC)). ctrl = peri-tumoral non-malignant tissue; canc = cancer tissue; SEM = standard error of mean

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