Table 3 Risk of second primary cancer after primary POFT cancer diagnosis according to histology
Histology | Serous | Mucinous | Endometrioid | Clear cell | Transitional cell | Carcinosarcoma | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
SIR | CI | SIR | CI | SIR | CI | SIR | CI | SIR | CI | SIR | CI | |
Leukaemia | 4.77# | (2.83–7.54) | 1.14 | (0.14–4.11) | 0.00 | (0.00–3.95) | 3.48 | (0.42–12.58) | 0.00 | (0.00–37.27) | 0.00 | (0.00–127.79) |
Urinary bladder | 1.81 | (0.59–4.22) | 1.68 | (0.20–6.06) | 4.59 | (0.95–13.43) | 0.00 | (0.00–11.77) | 0.00 | (0.00–51.86) | 0.00 | (0.00–128.39) |
Lung, bronchus | 1.08 | (0.71–1.58) | 3.59# | (2.52–4.98) | 1.54 | (0.70–2.92) | 2.51# | (1.08–4.94) | 1.52 | (0.0–8.47) | 0.00 | (0.00–15.84) |
Rectum, rectosigmoid junction | 1.54# | (1.03–2.23) | 1.22 | (0.56–2.32) | 1.84 | (0.79–3.62) | 0.39 | (0.01–2.19) | 2.06 | (0.05–11.5) | 0.00 | (0.00–24.49) |
Thyroid | 1.27# | (1.03–1.55) | 1.26 | (0.93–1.68) | 1.77# | (1.24–2.45) | 1.17 | (0.70–1.83) | 2.86# | (1.05–6.22) | 0.00 | (0.00–9.17) |
Colon | 1.31 | (0.99–1.7) | 1.82# | (1.23–2.58) | 2.56# | (1.67–3.75) | 0.85 | (0.28–1.98) | 2.62 | (0.54–7.65) | 2.75 | (0.07–15.33) |
Ascending colon | 1.01 | (0.44–1.99) | 2.93# | (1.34–5.57) | 2.73 | (0.89–6.37) | 1.97 | (0.24–7.11) | 0.00 | (0.00–17.3) | 14.02 | (0.35–78.11) |
Transverse colon | 0.62 | (0.08–2.24) | 3.97# | (1.29–9.27) | 6.68# | (2.17–15.59) | 4.77 | (0.58–17.24) | 0.00 | (0.00–42.6) | 0.00 | (0.00–126.37) |
Descending colon | 1.01 | (0.51–1.81) | 1.41 | (0.52–3.07) | 1.94 | (0.63–4.52) | 0.00 | (0.00–2.32) | 3.40 | (0.09–18.96) | 0.00 | (0.00–42.32) |
Rectum | 1.59# | (1.07–2.29) | 1.22 | (0.56–2.32) | 1.83 | (0.79–3.61) | 0.39 | (0.01–2.18) | 2.06 | (0.05–11.47) | 0.00 | (0.00–24.43) |
Other and unspecified | 2.34 | (0.86–5.09) | 1.78 | (0.22–6.45) | 4.84 | (1.00–14.14) | 0.00 | (0.00–11.74) | 15.06 | (0.38–83.91) | 0.00 | (0.00–148.5) |
Female breast | 1.58# | (1.26–1.97) | 0.78 | (0.47–1.22) | 1.38 | (0.83–2.16) | 0.48 | (0.16–1.12) | 1.42 | (0.17–5.14) | 3.60 | (0.09–20.08) |
Kidney parenchyma | 1.75 | (0.75–3.44) | 1.09 | (0.13–3.95) | 0.00 | (0.00–3.35) | 2.85 | (0.34–10.29) | 0.00 | (0.00–29.83) | 0.00 | (0.00–104.36) |
Renal pelvis, other urinary | 3.37 | (0.92–8.63) | 2.15 | (0.05–11.98) | 0.00 | (0.00–13.70) | 0.00 | (0.00–27.27) | 0.00 | (0.00–117.11) | 0.00 | (0.00–310.28) |
Pancreas | 1.01 | (0.46–1.92) | 1.95 | (0.78–4.02) | 1.95 | (0.53–4.98) | 0.00 | (0.00–3.49) | 0.00 | (0.00–15.72) | 0.00 | (0.00–42.09) |
Non-Hodgkin lymphoma | 1.04 | (0.42–2.15) | 1.06 | (0.22–3.09) | 0.00 | (0.00–2.27) | 0.00 | (0.00–3.61) | 0.00 | (0.00–20.58) | 19.38 | (0.49–108.01) |
Bile ducts, other biliary | 1.37 | (0.75–2.31) | 0.72 | (0.15–2.11) | 1.69 | (0.46–4.34) | 3.45 | (0.94–8.83) | 0.00 | (0.00–13.89) | 9.79 | (0.25–54.55) |
Stomach | 0.88 | (0.62–1.22) | 1.14 | (0.70–1.77) | 0.91 | (0.42–1.73) | 0.36 | (0.04–1.28) | 0.00 | (0.00–3.44) | 0.00 | (0.00–10.67) |
Liver | 0.84 | (0.42–1.51) | 0.19 | (0.00–1.08) | 0.00 | (0.00–1.19) | 1.71 | (0.35–5.00) | 0.00 | (0.00–10.68) | 9.41 | (0.24–52.43) |
Gallbladder | 0.38 | (0.05–1.38) | 0.92 | (0.11–3.33) | 1.63 | (0.20–5.87) | 0.00 | (0.00–6.08) | 0.00 | (0.00–27.04) | 0.00 | (0.00–71.35) |
Small intestine | 2.63 | (0.54–7.69) | 2.17 | (0.05–12.08) | 0.00 | (0.00–13.56) | 0.00 | (0.00–23.26) | 0.00 | (0.00–123.21) | 0.00 | (0.00–382.12) |
All excluding POFT | 1.26# | (1.15–1.39) | 1.26# | (1.09–1.45) | 1.64# | (1.38–1.93) | 0.98 | (0.74–1.27) | 1.31 | (0.68–2.29) | 2.80# | (1.13–5.77) |