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Fig. 5 | BMC Cancer

Fig. 5

From: Daphnane diterpenes inhibit the metastatic potential of B16F10 murine melanoma cells in vitro and in vivo

Fig. 5

Effect of gnidilatidin (0.1 μM) on wound healing, cell adhesion, and Mitf expression in B16F10 melanoma cell lines. a Scratched cell monolayer images for the wound healing assay results (wound healing assay results; b Cell adhesion assay results evaluated by performing the MTT assay on B16 cells cultured in fibronectin-coated 96-well plates; c Relative gene expression of Mmp2, Mmp9, and Cd44 genes; d Relative gene expression of Mitf; e Relative gene expression of tyrosinase (Tyr), c tyrosinase-related protein 1 (Trp1), dopachrome tautomerase (Dct), and (f) Ras-related protein (Rab27a), determined using TaqMan real-time quantitative PCR; g Melanin content of B16 cells. Results represent the mean ± SD of triplicate samples. *Statistically significant (P ≤ 0.05) difference between treated cells and control. **Statistically significant (P ≤ 0.01) difference between treated cells and control

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BMC Cancer

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