Fig. 3
The DCE-MRI results in the three groups. a The Ktrans maps derived from DCE-MRI on pre-treatment and after 15-day treatment in the three groups. As shown in the pictures, the blood supplies of the tumor margins were more abundant (red/green) than the central parts (blue) before treatment. Nevertheless, some differences emerged over 15 days of handling. The blood supply was more adequate in the control group, and the other two groups appeared to have nearly opposite distribution tendencies, especially the combination group. The quantitative analysis results further confirmed these changes and showed striking differences in Ktransb among the three groups before and after treatment. The changing tendencies were also derived from ANOVA