Skip to main content
Fig. 2 | BMC Cancer

Fig. 2

From: A novel approach to monitoring the efficacy of anti-tumor treatments in animal models: combining functional MRI and texture analysis

Fig. 2

The multi-b-value DWI results in the three groups. a The DWI and ADC map of pre-treatment and after 7- and 15-day treatment with different therapies. The subcutaneous tumor (white arrow) was implanted near the bladder (red arrow). As seen from the ADC map, water molecular diffusion was much lower in the tumors (blue) than in the bladder (red). The tumor region always showed lower diffusion in the control group. However, after 7 days of anti-tumor therapies, the limitations of water diffusion improved in both the paclitaxel and the combination groups (the tumor central areas showed a slightly higher green signal). Furthermore, this improvement was more obvious in the combination group after 15 days of treatment. Meanwhile, marked diversities were observed in ADCslow (b) and perfusion fraction (f) (c) among the three groups before and after treatment. The changing tendencies were derived from ANOVA, which reflected the variations after 15 days of treatment according to their own separate patterns

Back to article page