Incidence and risk factors of subsyndromal delirium after curative resection of gastric cancer

BMC Cancer

Table 2 Demographic and clinical characteristics of patients

Variable	No delirium (n = 143)	Subsyndromal delirium (n = 19)
Variable	Mean ± SD or n (%)		p value^a
Age (years)	61.31 ± 10.82	70.11 ± 7.49	0.001^*
Age ≥ 70	35 (24.5%)	11 (57.9%)	0.002^*
Male	91 (63.6%)	14 (73.7%)	0.389
Education level, ≤9 years^b	38 (28.6%)	12 (63.2%)	0.003^*
Body mass index (cm/kg²)	22.55 ± 3.08	23.46 ± 3.12	0.230
> 25	26 (18.2%)	4 (21.1%)	0.756
< 18.5	13 (9.1%)	1 (5.3%)	1.000
CCI (except age)			1.000
2–3	128 (89.5%)	17 (89.5%)
≥ 4	15 (10.5%)	2 (10.5%)
Preop midazolam use for anaesthesia-assisted gastroscopy	37 (26.1%)	4 (21.1%)	0.783
Pathological staging
0^c	4 (2.8%)	1 (5.3%)
I	104 (72.7%)	12 (63.2%)
II	22 (15.4%)	2 (10.5%)
III	12 (8.4%)	3 (15.8%)
IV	1 (0.7%)	1 (5.3%)
Surgical procedure			0.563
Laparoscopic	113 (79.0%)	14 (73.7%)
Open	30 (21.0%)	5 (26.3%)
Resection type
Total gastrectomy	33 (23.1%)	4 (21.1%)
Distal gastrectomy	77 (53.8%)	13 (68.4%)
Proximal gastrectomy	4 (2.8%)	0
Pylorus-preserving gastrectomy	29 (20.3%)	2 (10.5%)
Anaesthesia time (minutes)	266.47 ± 57.57	287.95 ± 45.03	0.120
Highest quartile	34 (23.8%)	5 (26.3%)	0.780
Main anaesthetic agent			0.767
Sevoflurane or desflurane (inhalants)	112 (78.3%)	16 (84.2%)
Propofol (TIVA)	31 (21.7%)	3 (15.8%)
Intraoperative analgesic agent			1.000
Remifentanil	131 (91.6%)	18 (94.7%)
Fentanyl	12 (8.4%)	1 (5.3%)

Abbreviations: SD standard deviation, CCI Charlson Comorbidity Index, preop preoperative, TIVA total intravenous anaesthesia
^aContinuous variables were analysed with independent t-tests, while categorical variables were analysed with chi-squared tests or Fisher’s exact tests
^bMissing data were excluded from the analysis (10 patients for the education level)
^cAmong the five patients with pathological stage 0, four patients were treated with endoscopic resection before admission for surgery and one patient was treated with neoadjuvant chemotherapy
^*p < 0.01

ISSN: 1471-2407