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Table 6 Association of tumoral BRD4 expression with IHC markers

From: Tumoral BRD4 expression in lymph node-negative breast cancer: association with T-bet+ tumor-infiltrating lymphocytes and disease-free survival

Marker†

BRD4/low

%

BRD4/high

%

P-value**

(n = 143)a

(n = 469)a

Number

Number

Her2

 Negative

129

92.8

414

93.2

0.8587

 Positive

10

7.2

30

6.8

 

ER

 Negative

35

29.2

109

28.1

0.8196

 Positive

85

70.8

279

71.9

 

PR

 Negative

59

49.6

167

42.2

0.1533

 Positive

60

50.4

229

57.8

 

EGFR

 Negative

117

96.7

376

93.3

0.1931

 Positive

4

3.3

27

6.7

 

CK5

 Negative

105

85.4

341

80.4

0.2137

 Positive

18

14.6

83

19.6

 

Ki67

  < 14%

64

54.7

144

37.4

0.0009

  > =14%

53

45.3

241

62.6

 
  1. **from Chi-Square or Fisher’s exact test
  2. aIHC marker data are not available for some tumors