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Table 2 Biomarker status in regional and distant metastases collected from cats with mammary carcinoma

From: CXCR4 and its ligand CXCL12 display opposite expression profiles in feline mammary metastatic disease, with the exception of HER2-overexpressing tumors

Regional Metastases Distant Metastases
Biomarker Axillary LN
(n = 18)
Retromammary LN
(n = 29)
Biomarker Lung
(n = 20)
Liver
(n = 7)
PR status PR status
 Negative 8 (44.4) 16 (55.2) Negative 14 (70.0) 6 (85.7)
 Positive 10 (55.6) 13 (44.8) Positive 6 (30.0) 1 (14.3)
ER status ER status
 Negative 8 (44.4) 24 (82.8) Negative 14 (70.0) 7 (100)
 Positive 10 (55.6) 5 (17.2) Positive 6 (30.0) 0 (0.0)
HER2 HER2
 Negative 13 (72.2) 20 (69.0) Negative 20 (100) 7 (100)
 Positive 5 (27.8) 9 (31.0) Positive 0 (0.0) 0 (0.0)
Ki-67 index Ki67 index
 Low (<14%) 2 (11.1) 4 (13.8) Low (<14%) 7 (35.0) 2 (28.6)
 High (≥14%) 16 (88.9) 25 (86.2) High (≥14%) 13 (65.0) 5 (71.4)
  1. LN Lymph nodes
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