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Table 2 Biomarker status in regional and distant metastases collected from cats with mammary carcinoma

From: CXCR4 and its ligand CXCL12 display opposite expression profiles in feline mammary metastatic disease, with the exception of HER2-overexpressing tumors

Regional Metastases

Distant Metastases

Biomarker

Axillary LN

(n = 18)

Retromammary LN

(n = 29)

Biomarker

Lung

(n = 20)

Liver

(n = 7)

PR status

PR status

 Negative

8 (44.4)

16 (55.2)

Negative

14 (70.0)

6 (85.7)

 Positive

10 (55.6)

13 (44.8)

Positive

6 (30.0)

1 (14.3)

ER status

ER status

 Negative

8 (44.4)

24 (82.8)

Negative

14 (70.0)

7 (100)

 Positive

10 (55.6)

5 (17.2)

Positive

6 (30.0)

0 (0.0)

HER2

HER2

 Negative

13 (72.2)

20 (69.0)

Negative

20 (100)

7 (100)

 Positive

5 (27.8)

9 (31.0)

Positive

0 (0.0)

0 (0.0)

Ki-67 index

Ki67 index

 Low (<14%)

2 (11.1)

4 (13.8)

Low (<14%)

7 (35.0)

2 (28.6)

 High (≥14%)

16 (88.9)

25 (86.2)

High (≥14%)

13 (65.0)

5 (71.4)

  1. LN Lymph nodes