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Table 3 Frequency of positivity of carcinoma cells for connexin43, MAD, Twist, vimentin, PCLγ, Tks5, and CXCR4 in paired primary tumors and metastasis of predominantly AC and SCC

From: Bulk tumour cell migration in lung carcinomas might be more common than epithelial-mesenchymal transition and be differently regulated

Protein

Primary tumor (%)

Metastasis (%)

Significance

Connexin 43

28.8 ± 34.2

25.4 ± 29.9

p 0.4

MAD

38.8 ± 30.1

32.2 ± 21.9

p 0.3

TWIST

23.8 ± 25.7

52.6 ± 27.6

p < 0.0001

Vimentin

2.1 ± 6.6

18.3 ± 30.7

p 0.005

PLCγ

17.6 ± 18.9

29.8 ± 20.1

p 0.02

Tks5

5.1 ± 6.3

14.3 ± 18.8

p 0.008

CXCR4

6.2 ± 12.1

4.7 ± 12.3

p 0.4

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BMC Cancer

ISSN: 1471-2407

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