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Table 1 Patient characteristics

From: Genomic alterations accompanying tumour evolution in colorectal cancer: tracking the differences between primary tumours and synchronous liver metastases by whole-exome sequencing

Characteristics

n = 21

Age

Median 68 (38–84)

Gender

 Male

12 (57%)

 Female

9 (43%)

Primary tumour location

 Right

9 (43%)

 Left

12 (57%)

Resection

 Concurrent

5 (24%)

 Subsequent – liver first

5 (24%)

 Subsequent – primary first

11 (52%)

Time between resections

Median 36 days

Treatment

 Chemonaïve

11 (52%)

 Both tumours

7 (33%)

 Only metastasis

2 (10%)

 Only primary

1 (5%)

Neoadjuvant treatment

 CAPOX

2 (10%)

 CAPOX + bevacizumab

2 (10%)

 FOLFIRI + cetuximab

1 (5%)

 FOLFOX + cetuximab

2 (10%)

Between resections

 CAPOX

2 (10%)

 FOLFOX

1 (5%)

Number metastases

Median 2 (1–5)

Microsatellite stability

21 (100%)

Tumour stage

 Stage IV

21 (100%)

Tumour differentiation

 Low

2 (10%)

 High

19 (90%)

  1. CAPOX denotes capecitabine and oxaliplatin, FOLFIRI signifies 5-fluorouracil and irinotecan; and FOLFOX indicates 5-fluorouracil and oxaliplatin