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Table 2 Comparisons of clinical characteristics between patients with and without ctDNA present (N = 32)

From: Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients

  ctDNA+ ctDNA- P value
(n = 23) (n = 9)
Gender
 Male 85.0 (17) 15.0 (3)* 0.05*
 Female 50.0 (6) 50.0 (6)  
Age
 Median years (range) 58 (25–78) 62 (34–83) 0.24
Stage
 M1a or b 16.7 (1) 83.3 (5) 0.03*
 M1c 84.6 (22) 15.4 (4)  
Performance status, ECOG
 0 69.6 (16) 30.4 (5) 0.68
  > 0.99 63.6 (7) 36.4 (4)  
LDH
 Not elevated 63.6 (7) 36.4 (4) 0.60
 Elevated 85.7 (6) 14.3 (1)  
 Not available 71.4 (10) 28.6 (4)  
  1. Abbreviation: ECOG Eastern Cooperative Oncology Group, LDH Lactate dehydrogenase. *Significant difference p < 0.05