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Table 2 Comparisons of clinical characteristics between patients with and without ctDNA present (N = 32)

From: Correlation between circulating tumour DNA and metabolic tumour burden in metastatic melanoma patients

 

ctDNA+

ctDNA-

P value

(n = 23)

(n = 9)

Gender

 Male

85.0 (17)

15.0 (3)*

0.05*

 Female

50.0 (6)

50.0 (6)

 

Age

 Median years (range)

58 (25–78)

62 (34–83)

0.24

Stage

 M1a or b

16.7 (1)

83.3 (5)

0.03*

 M1c

84.6 (22)

15.4 (4)

 

Performance status, ECOG

 0

69.6 (16)

30.4 (5)

0.68

  > 0.99

63.6 (7)

36.4 (4)

 

LDH

 Not elevated

63.6 (7)

36.4 (4)

0.60

 Elevated

85.7 (6)

14.3 (1)

 

 Not available

71.4 (10)

28.6 (4)

 
  1. Abbreviation: ECOG Eastern Cooperative Oncology Group, LDH Lactate dehydrogenase. *Significant difference p < 0.05