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Table 4 Univariate and Multivariate Cox analysis for Overall survival and Event-Free Survival in non-metastatic patients

From: Outcome of inflammatory breast cancer in Moroccan patients: clinical, molecular and pathological characteristics of 219 cases from the National Oncology Institute (INO)

Parameters

Event Free Survival

Overall Survival

Univariate analysis

Multivariate analysis

Univariate analysis

HR

95% CI

p

HR

95% CI

p

HR

95% CI

p

Side

 Right breast

1

  

1

  

1

  

 Left breast

1.92

1.07–3.44

0.02

2.87

0.98–8.42

0.05

1.36

0.61–3.01

0.44

 Bilateral

10.32

1.32–80.47

0.02

–

–

–

5.14

0.65–40.65

0.12

Obesitya

 No

1

  

1

  

1

  

 Yes

1.36

0.72–2.54

0.33

1.45

0.55–3.85

0.44

1.80

0.76–4.27

0.17

SBR Grade

 I

1

     

1

  

 II

0.63

0.18–2.16

0.46

   

0.67

0.14–3.09

0.61

 III

1.33

0.40–4.38

0.63

–

–

–

1.00

0.22–4.48

0.99

N status

 N-

1

     

1

  

 N+

1.55

0.79–3.04

0.19

–

–

–

1.55

0.61–3.91

0.35

Agea

 ˂30y

1

  

1

  

1

  

 31–40

0.89

0.29–2.67

0.84

0.24

0.03–1.86

0.17

2.60

0.32–20.76

0.36

 41–50

0.66

0.22–1.97

0.46

0.20

0.02–1.60

0.12

1.29

0.16–10.42

0.81

 ˃50y

0.62

0.20–1.95

0.46

0.06

0.00–0.61

0.01

2.18

0.25–18.36

0.47

ER

 Negative

1

     

1

  

 Positive

0.69

0.38–1.27

0.23

–

–

–

2.05

0.85–4.98

0.11

PgR

 Negative

1

     

1

  

 Positive

0.88

0.46–1.66

0.69

–

–

–

1.03

0.42–2.53

0.94

Her2

 Negative

1

     

1

  

 Positive

0.77

0.35–1.70

0.53

–

–

–

0.42

0.04–3.81

0.44

Molecular subtypea

 Luminal A

1

  

1

  

1

  

 Luminal B Her2 –

2.57

0.68–9.64

0.16

0.86

0.15–4.82

0.86

2.57

0.78–2.60

0.98

 Luminal B Her2 +

1.78

0.59–5.34

0.29

0.31

0.07–1.34

0.11

0.43

0.04–4.23

0.47

 Her2

0.57

0.06–4.91

0.61

0.11

0.01–1.18

0.06

0.57

0.05–3.81

0.98

 Triple negative

3.54

1.13–11.05

0.02

1.72

0.47–6.31

0.41

1.99

1.10–10.00

0.96

Surgerya

 No

1

  

1

  

1

  

 Yes

0.73

0.39–1.39

0.34

1.13

0.37–3.49

0.82

0.62

0.23–1.70

0.36

Radiotherapya

 No

1

  

1

  

1

  

 Yes

1.20

0.9–1.6

0.21

0.88

0.28–2.73

0.82

1.23

0.81–1.87

0.32

SERM treatment

 No

1

  

1

  

1

  

 Yes

0.48

0.07–0.59

0.01

0.09

0.01–0.72

0.02

1.01

0.69–1.49

0.92

  1. a: variables being adjusted for the multivariate model; significant p values are in boldface
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BMC Cancer

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