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Table 4 Univariate and Multivariate Cox analysis for Overall survival and Event-Free Survival in non-metastatic patients

From: Outcome of inflammatory breast cancer in Moroccan patients: clinical, molecular and pathological characteristics of 219 cases from the National Oncology Institute (INO)

Parameters Event Free Survival Overall Survival
Univariate analysis Multivariate analysis Univariate analysis
HR 95% CI p HR 95% CI p HR 95% CI p
Side
 Right breast 1    1    1   
 Left breast 1.92 1.07–3.44 0.02 2.87 0.98–8.42 0.05 1.36 0.61–3.01 0.44
 Bilateral 10.32 1.32–80.47 0.02 5.14 0.65–40.65 0.12
Obesitya
 No 1    1    1   
 Yes 1.36 0.72–2.54 0.33 1.45 0.55–3.85 0.44 1.80 0.76–4.27 0.17
SBR Grade
 I 1       1   
 II 0.63 0.18–2.16 0.46     0.67 0.14–3.09 0.61
 III 1.33 0.40–4.38 0.63 1.00 0.22–4.48 0.99
N status
 N- 1       1   
 N+ 1.55 0.79–3.04 0.19 1.55 0.61–3.91 0.35
Agea
 ˂30y 1    1    1   
 31–40 0.89 0.29–2.67 0.84 0.24 0.03–1.86 0.17 2.60 0.32–20.76 0.36
 41–50 0.66 0.22–1.97 0.46 0.20 0.02–1.60 0.12 1.29 0.16–10.42 0.81
 ˃50y 0.62 0.20–1.95 0.46 0.06 0.00–0.61 0.01 2.18 0.25–18.36 0.47
ER
 Negative 1       1   
 Positive 0.69 0.38–1.27 0.23 2.05 0.85–4.98 0.11
PgR
 Negative 1       1   
 Positive 0.88 0.46–1.66 0.69 1.03 0.42–2.53 0.94
Her2
 Negative 1       1   
 Positive 0.77 0.35–1.70 0.53 0.42 0.04–3.81 0.44
Molecular subtypea
 Luminal A 1    1    1   
 Luminal B Her2 – 2.57 0.68–9.64 0.16 0.86 0.15–4.82 0.86 2.57 0.78–2.60 0.98
 Luminal B Her2 + 1.78 0.59–5.34 0.29 0.31 0.07–1.34 0.11 0.43 0.04–4.23 0.47
 Her2 0.57 0.06–4.91 0.61 0.11 0.01–1.18 0.06 0.57 0.05–3.81 0.98
 Triple negative 3.54 1.13–11.05 0.02 1.72 0.47–6.31 0.41 1.99 1.10–10.00 0.96
Surgerya
 No 1    1    1   
 Yes 0.73 0.39–1.39 0.34 1.13 0.37–3.49 0.82 0.62 0.23–1.70 0.36
Radiotherapya
 No 1    1    1   
 Yes 1.20 0.9–1.6 0.21 0.88 0.28–2.73 0.82 1.23 0.81–1.87 0.32
SERM treatment
 No 1    1    1   
 Yes 0.48 0.07–0.59 0.01 0.09 0.01–0.72 0.02 1.01 0.69–1.49 0.92
  1. a: variables being adjusted for the multivariate model; significant p values are in boldface
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