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Fig. 7 | BMC Cancer

Fig. 7

From: 3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model

Fig. 7

Effect of 3AOA on tumor-induced lymphangiogenesis in a VEGF-A-induced oral cancer sentinel lymph node animal model. a, Lymphatic vessel density values in tumor and SLN sections were measured by immunohistochemical analysis using anti-LYVE-1 antibody. All sections were digitalized and images were captured under 200× objective magnification. Scale bar = 200 μm. b-c, Immunohistochemical intensity values of LYVE-1 from captured images of tumors and SLN were analyzed via the Image J program and represented as a bar diagram. Data are presented as a mean ± S.D. (*p < 0.05, ***p < 0.001). T = tumor; SLN = Sentinel lymph node

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BMC Cancer

ISSN: 1471-2407

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