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Fig. 6 | BMC Cancer

Fig. 6

From: 3-O-Acetyloleanolic acid inhibits VEGF-A-induced lymphangiogenesis and lymph node metastasis in an oral cancer sentinel lymph node animal model

Fig. 6

Effects of 3AOA on tumor growth, and sentinel lymph node enlargement and lymph node metastasis in a VEGF-A-induced oral cancer sentinel lymph node animal model. a, Tumor (tongue) and SLN sections of mice of each group were analyzed using hematoxylin and eosin staining, and immunohistochemical analysis with anti-cytokeratin antibody. All tumor sections were digitized, and microscopic images were captured under a 100× objective magnification. Scale bar = 200 μm. All SLN sections were digitized and images were captured under 200× objective magnification. Scale bar = 200 μm. b-c, Tumor volume and SLN volume were measured using a caliper. Data are presented as a mean ± S.D. (**p < 0.01, ***p < 0.001). T = tumor; SLN = Sentinel lymph node

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